0918. Grey matter perfusion is preserved during normotensive hypovolaemia, despite reductions in total cerebral blood flow: evidence of local, pressure independent, intra-cerebral vascular autoregulatory response

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0918. Grey matter perfusion is preserved during normotensive hypovolaemia, despite reductions in total cerebral blood flow: evidence of local, pressure independent, intra-cerebral vascular autoregulatory response

Methods Eleven healthy volunteers (20-31 years; 8-male 3-female) underwent MRI studies with a lower body negative pressure (LBNP) chamber. Imaging included quantitative phase contrast angiographic (PCA) measurements of blood volume flow in the carotid and vertebral arteries and ASL of the whole brain. An ASL sequence followed by PCA acquisition was performed at rest (control) and under -20mmHg ...

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Cerebral Blood Flow Influence of Changes in Blood Pressure on Cerebral Perfusion and Oxygenation

Cerebral autoregulation (CA) is a critical process for the maintenance of cerebral blood flow and oxygenation. Assessment of CA is frequently used for experimental research and in the diagnosis, monitoring, or prognosis of cerebrovascular disease; however, despite the extensive use and reference to static CA, a valid quantification of “normal” CA has not been clearly identified. While controlli...

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Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains.

The dynamics of the cerebral vascular response to blood pressure changes in hypertensive humans is poorly understood. Because cerebral blood flow is dependent on adequate perfusion pressure, it is important to understand the effect of hypertension on the transfer of pressure to flow in the cerebrovascular system of elderly people. Therefore, we examined the effect of spontaneous and induced blo...

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Relationships between cerebral perfusion pressure and regional cerebral blood flow in patients with severe neurological disorders.

Relationships Between Cerebral Perfusion Pressure and Regional Cerebral Blood Flow in Patients With Severe Neurological Disorders • Three patients, one with a recurrent brain tumor, one with a severe brain contusion, and one with a brain abscess, are described who had continuous monitoring of the intracranial pressure with epidural and/or ventricular pressure transducers, continuous monitoring ...

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Abnormal cerebral blood flow in methamphetamine abusers assessed by brain perfusion single emission computed tomography

Introduction:Amphetamines are central nervous system (CNS) stimulant substances and amphetamine abuse is considered a growing problem in our country. Previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. The aim of current study was evaluating regional cerebral blood flow (rCBF) disturbances in methamphetamine (MA) abuser...

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ژورنال

عنوان ژورنال: Intensive Care Medicine Experimental

سال: 2014

ISSN: 2197-425X

DOI: 10.1186/2197-425x-2-s1-o26